News

Follow the latest news on Bioqube Ventures, the Bioqube Factory Fund and our portfolio companies here.

22/04/2024

SynOx Therapeutics announces $75m Series B round to fund Phase 3 trial of potential best-in-class treatment for TGCT

Dublin, Ireland and Oxford, UK, 22 April 2024: SynOx Therapeutics Limited (“SynOx” or the “Company”), the late-stage clinical biopharmaceutical company, is pleased to announce the close of a $75m Series B financing. The financing was co-led by Forbion, HealthCap and new investor Bioqube Ventures. The proceeds will be used to generate registrational Phase 3 clinical […]

04/04/2024

Egle Therapeutics to present novel immunocytokine preclinical data for EGL-001 with poster presentation at the 2024 AACR Annual Meeting

April 04, 2024 03:30 PM Eastern Daylight Time Egle Therapeutics to present novel immunocytokine preclinical data for EGL-001 with poster presentation at the 2024 AACR Annual Meeting In the poster, entitled “EGL-001 is a novel immunocytokine designed to specifically target and disarm T regulatory cells in the tumor microenvironment”. Egle scientists present evidence that EGL-001, […]

26/03/2024

Bicara Therapeutics Expands Clinical Team with Appointments of Jeltje Schulten, M.D., MBA, as SVP of Clinical and Medical Affairs and Rita Dalal, MBBS, MPH, as VP of Clinical Development

BOSTON, Mass., March 26, 2024 – Bicara Therapeutics, a clinical-stage biotechnology company developing dual-action biologics to elicit a potent and durable immune response, today announced the appointments of Jeltje Schulten, M.D., MBA, as SVP of clinical and medical affairs and Rita Dalal, MBBS, MPH, as vice president of clinical development. “With our first-in-class EGFR/TGF-β-trap bifunctional antibody, […]

20/03/2024

Primmune Therapeutics Secures $22.5 Million Contract from Defense Threat Reduction Agency (DTRA) to Advance PRTX007 for Treatment of Lassa Fever

– PRTX007 program to support DTRA’s efforts to establish biological defense solution against Lassa fever and other hemorrhagic viruses – SAN DIEGO, March 20, 2024 – Primmune Therapeutics, a biotech company harnessing the power of the innate immune system, today announced that it was awarded a $22,480,552 contract by the Defense Threat Reduction Agency (DTRA) […]

31/01/2024

Enhanc3D Genomics appoints Dr Daniel Turner as Chief Scientific Officer

Appointment forms part of ongoing plans for continued development of the GenLink3D genomics platform and formation of strategic commercial and academic partnerships Cambridge, UK, 31 January 2024 – Enhanc3D Genomics, a company developing disruptive technologies to unlock the 3D spatial genome for target and biomarker discovery, today announced the appointment of Dr Daniel Turner as Chief Scientific […]

12/12/2023

Bicara Therapeutics Announces Oversubscribed $165 Million Series C Financing

Proceeds to accelerate clinical development of first-in-class bifunctional EGFR/TGF-β inhibitor, BCA101, for multiple cancer types, including 1L HPV-negative recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) Presented positive interim clinical data at 2023 ASCO Annual Meeting and ESMO Congress 2023 from ongoing Phase 1/1b dose expansion study of BCA101 in combination with pembrolizumab demonstrating […]

23/10/2023

Bicara Therapeutics Presents Updated Interim Data from Ongoing Phase 1/1b Study of BCA101 in 1L HPV-negative Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) at ESMO Congress 2023

First-in-class bifunctional EGFR/TGF-β inhibitor, BCA101, in combination with pembrolizumab continues to demonstrate clinically meaningful preliminary anti-tumor activity consistent with previous results BOSTON, Mass., October 23, 2023 – Bicara Therapeutics, a clinical-stage biotechnology company developing dual-action biologics to elicit a potent and durable immune response, today announced the presentation of updated, positive interim data from its ongoing, […]

16/10/2023

Bicara Therapeutics Expands Board of Directors with Appointments of Kate Haviland and Scott Robertson

Boston, Mass., October 16, 2023 – Bicara Therapeutics, a clinical-stage biotechnology company developing dual-action biologics to elicit a potent and durable immune response, today announced the expansion of its board of directors with the appointments of biopharmaceutical industry veterans Kate Haviland and Scott Robertson. “Kate and Scott bring an impressive breadth of experience and leadership within […]

11/10/2023

Primmune Therapeutics to Present New Clinical Data from Phase 1 Study Evaluating PRTX007 at the 2023 American Association for the Study of Liver Diseases (AASLD) Annual Meeting

SAN DIEGO, October 11, 2023 – Primmune Therapeutics, a biotech company harnessing the power of the innate immune system, today announced the upcoming presentation of new clinical data from its Phase 1 study of PRTX007, an orally administered prodrug of a novel, small molecule toll-like receptor 7 (TLR7)-specific agonist, at the 2023 American Association for […]

21/09/2023

Anavo Therapeutics strengthens management team

The company appoints industry veteran Shaun McNulty as Chief Scientific Officer and welcomes R&D expert Anna Quattropani as Senior Vice President of Chemistry & Non-Clinical Development Leiden, The Netherlands – September 21, 2023 – Anavo Therapeutics, a global leader in unlocking the full therapeutic potential of phosphatase biology, announced the appointment of Shaun McNulty, DPhil, […]

25/07/2023

Bicara Therapeutics Expands Management Team with the Appointment of David Raben, M.D., as Chief Medical Officer

CAMBRIDGE, Mass., July 24, 2023 – Bicara Therapeutics, a clinical-stage biotechnology company developing dual-action biologics to elicit a potent and durable immune response, today announced the appointment of David Raben, M.D., as chief medical officer. Dr. Raben joins Bicara with more than 25 years of biopharma and academic translational oncology experience, having most recently served as […]

05/06/2023

Bicara Therapeutics’ First-in-class Bifunctional EGFR/TGF-β Inhibitor, BCA101, Demonstrates 65% ORR in Combination with Pembrolizumab in 1L HPV-negative Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Phase 1/1b results to be highlighted in an oral presentation at 2023 ASCO Annual Meeting CAMBRIDGE, Mass., June 5, 2023 – Bicara Therapeutics, a clinical-stage biotechnology company developing dual-action biologics to elicit a potent and durable immune response, today will present positive interim data from its ongoing, open-label Phase 1/1b dose expansion study of BCA101, a […]

02/05/2023

Anavo Therapeutics extends Seed Round to EUR 28 Million to Advance Pipeline of Novel Phosphatase Modulators Toward the Clinic

Leiden, The Netherlands, and Heidelberg, Germany, May 2, 2023 – Anavo Therapeutics, a global leader in unlocking the full therapeutic potential of human phosphatase biology, announced today an EUR 8.5 million seed round extension, adding MRL Ventures Fund as a new investor. All existing investors, M Ventures, INKEF, Taiho Ventures, and Bioqube Ventures, participated in the […]

18/04/2023

Primmune Therapeutics Presents New Clinical Data from Phase 1 Study Evaluating PRTX007 in Healthy Volunteers at the 2023 American Association for Cancer Research (AACR) Annual Meeting

— PRTX007 was shown to be well-tolerated with a favorable safety profile for all analyzed cohorts in the Phase 1 study — — Stable systemic immune induction was observed in the 750mg cohort, with CD8+ T cells and NK cell activation significantly increasing from pretreatment to end of dosing in all healthy volunteers (HVs) — — No […]

14/03/2023

Primmune Therapeutics to Present New Clinical Data from Phase 1 Study Evaluating PRTX007 at the 2023 American Association for Cancer Research (AACR) Annual Meeting

SAN DIEGO, March 14, 2023 – Primmune Therapeutics, a biotech company harnessing the power of the innate immune system to treat solid tumors in the advanced cancer setting and for the clearance of human papillomavirus and related pre-cancerous cervical lesions, today announced the upcoming presentation of new clinical data from its Phase 1 study of […]

06/03/2023

Bicara Therapeutics Announces Oversubscribed $108 Million Series B Financing to Advance Clinical-Stage Pipeline of Dual-Action Biologics to Treat Cancer

Financing will support future studies of lead program BCA101, currently in Phase 1/1b clinical development in head and neck cancer, and pipeline growth Financing co-led by Red Tree Venture Capital and RA Capital Management CAMBRIDGE, Mass., MARCH 6, 2023 — Bicara Therapeutics, a clinical-stage biotechnology company developing dual-action biologics to elicit a potent and durable […]

20/10/2022

Enhanc3D Genomics raises £10 million in Series A financing to advance GenLink3D proprietary technology platform

GenLink3DTM provides the first high-resolution mapping of DNA interactions in 3D space, enabling the vast array of non-coding genetic variations to be deciphered into actionable disease biomarkers and treatment targets Funds will be used to rapidly generate deep datasets of novel diagnostic signatures and candidate therapeutic targets across multiple immune-related diseases for internal and external […]

15/09/2022

TRIDEK-ONE CLOSES A €16 MILLION FINANCING ROUND TO DEVELOP FIRST-IN-CLASS IMMUNE CHECKPOINT AGONISTS

Financing led by Pureos Bioventures with significant participation from new and historical investors Funds will primarily be used to identify candidates to develop, conduct IND-enabling studies and further build the organization Tridek-One also appointed Laurence de Schoulepnikoff as chief executive officer and Erik van den Berg as chairman of the board of directors Paris, France, […]

26/05/2022

ENHANC3D GENOMICS Awarded QuickFire Challenge Grant

Awarded grant funding from Johnson & Johnson Innovation and one year of JLABS residency Functional genomics technology focused on the uncharted non-coding regions across the whole human genome Identification of 3D genetic interactions that are disease-associated to revolutionise target and biomarker identification Unique GenLink3DTM platform opens new opportunities for multiOMICs data integration in patient samples […]

30/11/2021

Lonza and Bioqube Ventures Sign a Framework Agreement for the Future Development and Manufacture of Biologics and Small Molecules for Bioqube’s Portfolio Companies

The five-year services agreement provides for the development and manufacturing of biologics and small molecules for portfolio companies of Bioqube Ventures The offering will accelerate timelines for the development and manufacturing of molecules and disruptive technologies, Lonza to support Bioqube Ventures with investment de-risking and providing development and manufacturing of drug substance and drug product […]

04/11/2021

Primmune Therapeutics Receives $8.4 Million in Second Tranche of Series A Financing

SAN DIEGO, November 4, 2021 – Primmune Therapeutics today announced that it has received $8.4 million in a second tranche of the Company’s Series A financing. The total proceeds for the equity raised in the Series A was $31.4 million. These funds will be used to support the further clinical development of PRTX007 as a […]

02/11/2021

Primmune Therapeutics Provides Update on Phase 1 Healthy Volunteer Study of PRTX007, A First in Class Novel Oral TherAjuvant™

SAN DIEGO, November 2, 2021 – Primmune Therapeutics today announced interim results from its Phase 1 study in healthy volunteers with PRTX007, a novel orally-administered, small molecule toll-like receptor 7 (TLR7) specific agonist for acute viral diseases, including SARS-CoV-2, and cancer. This double blind, placebo-controlled Phase 1 study is evaluating the safety, pharmacokinetics (PK), pharmacodynamics […]

26/10/2021

Egle Therapeutics raises 40 million € Series A to develop First-In-Class T-regulatory cells therapies based on Treg-starvers

LSP and Bpifrance, through its InnoBio 2 Fund, co-led international investor syndicate Egle Therapeutics SAS (Egle), an emerging biotechnology company focused on developing First-In- Class immunotherapies targeting immune suppressor regulatory T-cells (Tregs) for oncology and autoimmune diseases, today announces that it has completed a €40M ($46.4M) Series A financing. The Series A was co-led by […]

16/08/2021

Anavo Therapeutics to Establish R&D Hub in World-Leading Cancer Research Cluster

Leiden, The Netherlands, and Heidelberg, Germany, August 16, 2021 – Anavo Therapeutics, a global leader in unlocking the full therapeutic potential of human phosphatase biology, today announced that the company has partnered with BioLabs Global, a developer and operator of premium co-working laboratories in the U.S. and Europe, to establish its R&D center as one of […]

24/06/2021

Anavo Therapeutics Strengthens Scientific Advisory Board with Industry-Leading Drug Discovery Experts in Oncology

Karl-Heinz Altmann, Andrew Mortlock and Gregg Siegal to join Anavo’s SAB Leiden, The Netherlands, June 24, 2021 – Anavo Therapeutics, a global leader in unlocking the full therapeutic potential of human phosphatase biology, today announced three key appointments to its Scientific Advisory Board in the persons of Karl-Heinz Altmann, currently Full Professor of Pharmaceutical Sciences […]

22/04/2021

Anavo Therapeutics Launches with EUR 20 Million Seed Financing to Create Industry-Leading Pipeline of Allosteric Phosphatase Modulators

Anavo Therapeutics Launches with EUR 20 Million Seed Financing to Create Industry-Leading Pipeline of Allosteric Phosphatase Modulators

09/03/2021

Primmune Therapeutics Strengthens Leadership Team with Key Appointments

SAN DIEGO, February 5, 2021 – Today, Primmune Therapeutics announced the appointment of Rich Daniels as Chief Operating Officer, Scott Zook as Senior Vice President, Global Manufacturing and Randy Adams as Senior Advisor, Commercial Development. “The appointments of Rich, Scott and Randy to the team build on the recent close of our Series A financing to support the […]

12/01/2021

Primmune Therapeutics Announces Close of Series A Financing

SAN DIEGO, January 12, 2021 – Today, Primmune Therapeutics announced the close of its Series A financing round with the addition of $4.0 million from Bioqube Ventures, a European life sciences venture capital firm. This brings the total of the Series A financing raise to $31.4 million. These funds will be used to support the development of PRTX007, […]

24/09/2020

Bioqube Ventures welcomes two seasoned professionals

Brussels/Hasselt, Belgium – 24th September 2020 – Bioqube Ventures, a European life sciences venture capital firm, today announces that Tom Heyman joins Bioqube Ventures as Operating Partner and Peter Verhaeghe will chair the LP and Advisory Committee of the Bioqube Factory Fund I. Bolstering the team with industry veterans Tom Heyman and Peter Verhaeghe will […]

10/06/2020

Bioqube Ventures launches Bioqube Factory Fund I

Bioqube Ventures announces today the first closing of Bioqube Factory Fund I, a new early stage venture capital fund focused on the development of therapeutic assets and technology platforms in Europe.